The Worcester Regional MRC provides medical volunteer capacity to 48 communities in central Massachusetts. (Click here to view a map of the region)
Residential populations (US Census Bureau 2008-2012 American Community Survey):
| Central Division | Northeast Division | Southeast Division: | Southwest Division: |
| | | |
| Boylston: 4,341 | Ashby: 3,066 | Bellingham: 16,304 | Auburn: 16,221 |
| Holden: 17,361 | Ayer: 7,480 | Blackstone: 9,030 | Brimfield: 3,610 |
| Leicester: 10,988 | Berlin: 2,866 | Douglas: 8,432 | Brookfield: 3,378 |
| Millbury: 13,270 | Bolton: 4,905 | Franklin: 32,148 | Charlton: 12,947 |
| Paxton: 4,812 | Dunstable: 3,190 | Hopedale: 5,911 | Dudley: 11,401 |
| Shrewsbury: 35,583 | Groton: 10,687 | Medway:12,742 | East Brookfield: 2,152 |
| West Boylston: 7,697 | Harvard: 6,505 | Mendon: 5,827 | Holland: 2,477 |
| Worcester: 181,473 | Lancaster: 7,935 | Milford: 28,002 | North Brookfield: 4,681 |
| Lunenburg: 10,356 | Millville: 3,168 | Oxford: 13,713 |
| Northborough: 14,407 | Upton: 7,485 | Spencer: 11,713 |
| Pepperell: 11,537 | Uxbridge: 13,382 | Southbridge: 16,775 |
| Shirley: 7,352 | | Sturbridge: 9,230 |
| Townsend: 8,981 | | Wales: 1,990 |
| | | Warren: 5,116 |
| | | Webster: 16,760 |
| | | West Brookfield: 3,718 |
The number of people in the coverage area at any given time is subject to fluctuations in the work day, as well as seasonal differences (such as summer vacations). One of the key challenges for the region is the diversity of its multiple cultures. The corresponding range of lifestyles and attitudes toward health require flexible approaches to education and patient care.